The overall objective of the Animal Carcinogenesis Shared Resource is to provide the members of the Cancer Center with the ability to utilize animal carcinogenesis models in the implementation of their research projects. Animal in vivo experiments are required as a step of the processes of translational research by which the results of research done in the laboratory are used to develop new ways to diagnose and treat cancer.
Kawamori, Toshihiko, M.D., Ph.D.
Role: Director of Animal Carcinogenesis Shared Resource
"The facility will provide resources and expertise in animal tissue histology services including tissue processing, histology slide preparation with hematoxylin and eosin staining, and immunohistochemistry."
"The facility will collect animal tumor samples with adjacent normal counterparts along with histology sections from animal carcinogenesis experiments and try to establish primary animal tumor cell lines."
This service provides "the necessary facility and expertise for carcinogenesis models to support the research projects. The facility will provide resources and expertise in animal models of cancer, including colon, tongue (head & neck), breast, prostate, and liver carcinogenesis models using chemical carcinogens or genetically engineered mouse models."
"With his extensive expertise in the area of pathology, the facility’s director is able to provide the necessary infrastructure for this resource, which is novel and bridges basic science results to the patient’s bedside through pre-clinical studies."