The University of Hawaii Biorepository is a non-commercial, NIH-sponsored, core facility that provides biomedical researchers restricted access to human biological samples and clinical data.
The UH Biorepository contains three resources: 1) The Comprehensive Human Organ and Tissue Bank, 2) The Human Reproductive Biospecimen Repository, and 3) The INBRE III Biorepository and in vivo Model Resource. See below for more details.
For instructions on how to apply for access to our samples, please visit: uhbio.jabsom.hawaii.edu.
Member:
Astern, Joshua, Ph.D.
Role:
Manager
Associated with Hawaii’s Legacy of Life organ donation team, the Comprehensive Human Organ and Tissue Bank receives organs that are unfortunately not placed for transplant. The donor’s families consent to provide the organs for research, and the donor’s deidentified clinical information is uploaded into our database.
Flash frozen tissue:
-heart
-liver
-kidney
-lymph nodes
-spleen
-extensive clinical data and ethnicity information amended to each sample
The Comprehensive Human Organ and Tissue Bank is funded by a grant from the National Institute on Minority Health and Health - RCMI BRIDGES • G12 MD007601 (PI: Dr. M. Berry).
To date, more than 9,250 women-child pairs are contained within HiBR and approximately 3,000 specimens have been released to researchers. The clinical database that integrates with the biospecimen repository was developed as a Relational Database Management System (RDBMS). Presently, the maternal database tables contain nearly 400 variables for more than 8,500 women-infant pairs, with the accompanying infant data tables containing more than 80 variables.
-maternal DNA
-maternal plasma
-baby DNA
-umbilical cord serum
-flash frozen placenta
-FFPE placenta from several regions of the tissue
-flash frozen umbilical cord
-placental RNA (very limited "n", as this was a pilot project)
-extensive clinical data and ethnicity information amended to each sample
The Human Reproductive Biospecimen Repository is funded by a grant from the National Institute on Minority Health and Health Disparities • RMATRIX - 3U54MD007584-03S1 (PI: Dr. J Hedges).
Overlapping with the The University of Hawaii Biorepository, this resource has been designed to empower investigators with access to experimental resources that they would otherwise be unable to easily implement themselves, specifically non-UH-Manoa state institutions. UH-Hilo, Chaminade, HPU, and state community colleges.
The INBRE III Biorepository and in vivo Model Resource is funded by a grant from the National Institute General Medical Sciences • INBRE III • P20GM10346612 (PI: Dr. R Nichols).