Dr. Lau's laboratory is currently focused on the regulation of gap junctions by tyrosine protein kinases and novel, interacting cellular proteins. Gap junctions are one of four major types of intercellular junctions that are involved in establishing intercellular adhesion and communication. Gap junctions are unique because they enable the direct interchange of small molecules (<1000 daltons) between the cytoplasms of adjacent cells. This activity provides a form of intercellular signaling that is essential for the proper functioning of a variety of normal tissues.