Laboratory of Biocolloids and Biointerfaces

Summary:

We study fundamental colloid and surface science and its applications to areas of biomedical and biotechnological interest. In particular, we focus on the biophysical study of lung surfactant and other self-assembled phospholipid/protein monolayers/bilayers/multilayers; pulmonary toxicology of nanomaterials and nanoparticle-based pulmonary drug delivery; and the development of advanced surface tension and contact angle measurement methodologies. The techniques we use include Atomic Force Microscopy (AFM), Langmuir-Blodgett (LB) technique, and drop shape analysis. The goal of our study is to explore the fundamental nature of biocolloids and biointerfaces, and to apply this knowledge to biomedical and clinical practices through an interdisciplinary and translational approach.

Affiliations:

• College of Engineering, University of Hawaii at Manoa

People:

• PI: Zuo, Yi, Ph.D.
  

Resources:

Instruments

• Innova scanning probe microscope ( Scanning force microscope )
  

• Nima Technology Langmuir-Blodgett trough ( Langmuir-Blodgett Trough )
  

• Surface tension and contact angle measurement system ( Surface tension and contact angle measurement system )
  

Software

• Axisematic Drop Shape Analysis (ADSA) ( Software )
  

  Visual C++, Fortran. Please contact the PI if you are interested in the program.
  
  "DSA is an advanced software package capable of determining surface tension and contact angle from all three commonly used drop/bubble configurations: pendant drop, sessile drop, and captive bubble."

Web Links:

• http://www2.hawaii.edu/~yzuo/