The Pacific Research Center for Marine Biomedicine (PRCMB) at the University of Hawaii, led by Edward Laws and Richard Yanagihara, is conducting interdisciplinary research on harmful algal blooms, water- and vector-borne diseases, and marine-derived pharmaceuticals and probes. Knowledge gained from this research will advance national health and lead to improved strategies to reduce the burden of human diseases resulting from acute and chronic exposures to risks in the ocean environment.