The Rappé laboratory for aquatic microbial ecology is located at the Hawaii Institute of Marine Biology (HIMB), a research institute in the School of Ocean and Earth Science and Technology (SOEST) of the University of Hawaii at Manoa. The HIMB is located on Coconut Island in Kaneohe Bay, about a 30 minute drive from the main university campus.
Using a variety of approaches (genomics, molecular biology, microbial oceanography, and traditional microbiology), research in the Rappé Lab focuses on the diversity, evolutionary history, ecology, and physiology of microorganisms that inhabit coastal and open ocean seawater, corals and coral reef environments, and the deep subsurface biosphere.