Clinical trial
clinical trial
Randomized phase II study of docetaxel followed by vandetanib (ZD6474) vs. docetaxel plus vandetanib in patients with persistent or recurrent epithelial ovarian, fallopian tube, or primary peritoneal carcinoma
Intervention
Drug intervention
Intervention Type
drug intervention
has_intervention
Vandetanib
drug intervention
Vandetanib
Intervention
intervention
planned process
planned process
process
occurrent
entity
Drug intervention
drug intervention
Docetaxel
drug intervention
Docetaxel
Intervention
intervention
planned process
planned process
process
occurrent
entity
Contact
has contact
has_contact
Berenberg, Jeffrey
PI
has PI
has_PI
Topic
has topic
has_topic
ovarian cancer
Funded by
funded by
funded_by
SWOG
Phase
Phase 2 clinical trial
has phase
has_phase
Phase 2
Performed by
human study performed by
human_study_performed_by
Clinical Protocol & Data Management Shared Resource
http://www.clinicaltrials.gov/ct2/show/NCT00872989?term=S0904&rank=1
ClinicalTrials.gov url
ClinicalTrials.gov url
CTurl
RATIONALE: Vandetanib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. It is not yet known whether docetaxel is more effective when given alone or together with vandetanib.
PURPOSE: This randomized phase II trial is studying docetaxel given together with or without vandetanib to see how well it works in treating patients with persistent or recurrent ovarian epithelial cancer, fallopian tube cancer, or primary peritoneal cancer.
Resource Description
resource_description
Females age 18 and older with histologically confirmed ovarian epithelial, fallopian tube, or primary peritoneal carcinoma.
Study Population
study population
has_study_population
2011-06-29T19:20:43.282-05:00
awendicke (Annemarie Wendicke)
2011-09-23T11:14:05.485-05:00
workflow state
Published
nvasilevsky
cpealer
Interventional study
Research project
research project
Human Study
human study
human study
planned process
planned process
Quantitative human study
process
occurrent
entity