Temozolomide and radiation therapy with or without bevacizumab in treating patients with newly diagnosed glioblastoma

eagle-i ID

Resource Type

Properties

1. ClinicalTrials.gov url

   http://www.clinicaltrials.gov/ct2/show/NCT00884741?term=RTOG-0825&rank=1

2. Intervention

   Temozolide

3. Intervention

   Radiation therapy

4. Intervention

   Bevacizumab

5. Resource Description

   This randomized phase III trial is studying temozolomide and radiation therapy to compare how well they work when given together with or without bevacizumab in treating patients with newly diagnosed glioblastoma. (gliosarcoma closed to accrual as of 07-13-10).

6. Additional Name

   Phase III double-blind placebo-controlled trial of conventional concurrent chemoradiation and adjuvant temozolomide plus bevacizumab versus conventional concurrent chemoradiation and adjuvant temozolomide in patients with newly diagnosed glioblastoma

7. Contact

   Berenberg, Jeffrey

8. PI

   Berenberg, Jeffrey

9. Topic

   glioblastoma multiforme

10. Funded by

    Radiation Therapy Oncology Group

11. Phase

    Phase 3 clinical trial

12. Performed by

    Clinical Protocol & Data Management Shared Resource