eagle-i University of Hawaii at ManoaUniversity of Hawaii at Manoa
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Randomized phase III trial of adjuvant therapy comparing chemotherapy alone (six cycles of docetaxel plus cyclophosphamide or four cycles of doxorubicin plus cyclophosphamide followed by weekly paclitaxel) to chemotherapy plus trastuzumab in women with node- positive or high-risk node-negative her2-low invasive breast cancer

eagle-i ID

http://hawaii.eagle-i.net/i/00000130-ddbf-8d09-9953-50a980000000

Resource Type

  1. Clinical trial

Properties

  1. ClinicalTrials.gov url
    http://www.clinicaltrials.gov/ct2/show/NCT01275677?term=NSABP+B-47&rank=1
  2. Intervention
    Cyclophosphamide
  3. Intervention
    Docetaxel
  4. Intervention
    Doxorubicin hydrochloride
  5. Intervention
    Paclitaxel
  6. Intervention
    Trastuzumab
  7. Additional Topic(s)
    Antineoplastic combined chemotherapy protocols
  8. Resource Description
    RATIONALE: It is not yet known whether combination chemotherapy is more effective with trastuzumab in treating breast cancer. PURPOSE: This randomized phase III clinical trial is studying chemotherapy with or without trastuzumab after surgery to see how well they work in treating women with invasive breast cancer.
  9. Contact
    Berenberg, Jeffrey
  10. PI
    Berenberg, Jeffrey
  11. Topic
    breast cancer
  12. Study Population
    Females age 18 and older with a tumor that must be unilateral invasive adenocarcinoma of the breast on histologic examination.
  13. Website(s)
    http://www.cancer.gov/clinicaltrials/search/view?cdrid=692574&version=healthprofessional
  14. Funded by
    National Surgical Adjuvant Breast and Bowel Project
  15. Phase
    Phase 3 clinical trial
  16. Performed by
    Clinical Protocol & Data Management Shared Resource
 
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Provenance Metadata About This Resource Record
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The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016