Phase III clinical trial comparing trastuzumab given concurrently with radiation therapy and radiation therapy alone for women with HER2-positive ductal carcinoma in situ resected by lumpectomy

eagle-i ID

Resource Type

Properties

1. ClinicalTrials.gov url

   http://www.clinicaltrials.gov/ct2/show/NCT00769379?term=NSABP+B-43&rank=1

2. Intervention

   Trastuzumab

3. Intervention

   Radiotherapy

4. Additional Topic(s)

   Lumpectomy

5. Resource Description

   This randomized phase III trial is studying radiation therapy to see how well it works compared with or without trastuzumab in treating women with ductal carcinoma in situ who have undergone lumpectomy.

6. Contact

   Berenberg, Jeffrey

7. PI

   Berenberg, Jeffrey

8. Topic

   invasive ductal carcinoma

9. Study Population

   Women aged 18 years and older with histologically confirmed ductal carcinoma in situ (DCIS) who have have undergone resection by lumpectomy with no more than 120 days since the last surgery for excision of DCIS.

10. Website(s)

    http://www.cancer.gov/clinicaltrials/search/view?cdrid=615085&version=healthprofessional

11. Funded by

    National Surgical Adjuvant Breast and Bowel Project

12. Phase

    Phase 3 clinical trial

13. Performed by

    Clinical Protocol & Data Management Shared Resource