Randomized phase III study comparing 5-FU, leucovorin and oxaliplatin versus 5-FU, leucovorin, oxaliplatin and bevacizumab in patients with stage II colon cancer at high risk for recurrence to determine prospectively the prognostic value of molecular markers

eagle-i ID

Resource Type

Properties

1. ClinicalTrials.gov url

   http://www.clinicaltrials.gov/ct2/show/NCT00217737?term=E5202&rank=1

2. Intervention

   Bevacizumab

3. Intervention

   Fluorouracil

4. Intervention

   Leucovorin calcium

5. Intervention

   Oxaliplatin

6. Additional Topic(s)

   Antineoplastic combined chemotherapy protocols

7. Resource Description

   This randomized phase III trial is studying oxaliplatin, leucovorin, fluorouracil, and bevacizumab to see how well they work compared to oxaliplatin, leucovorin, and fluorouracil or observation only in treating patients who have undergone surgery for stage II colon cancer.

8. Contact

   Berenberg, Jeffrey

9. PI

   Berenberg, Jeffrey

10. Topic

    colon cancer

11. Study Population

    Males and females age 18 and over with histologically confirmed adenocarinoma of the colon that meets the criteria of Stage II carcinoma (T3 or T4).

12. Website(s)

    http://www.cancer.gov/clinicaltrials/featured/trials/ecog-e5202

13. Website(s)

    http://www.cancer.gov/clinicaltrials/search/view?cdrid=443410&version=healthprofessional

14. Funded by

    Cancer Trials Support Unit

15. Phase

    Phase 2 clinical trial

16. Performed by

    Clinical Protocol & Data Management Shared Resource