Phase III double blind, placebo controlled study of donepezil in the irradiated brain

eagle-i ID

Resource Type

Properties

1. ClinicalTrials.gov url

   http://www.clinicaltrials.gov/ct2/show/NCT00369785?term=NCT00369785&rank=1

2. Intervention

   Placebo

3. Intervention

   Donepezil

4. Additional Topic(s)

   Side effects of radiation therapy

5. Resource Description

   This randomized phase III trial is studying donepezil to see how well it works in lessening side effects of radiation therapy compared with a placebo in patients who have undergone radiation therapy for brain tumors.

6. Contact

   Berenberg, Jeffrey

7. PI

   Berenberg, Jeffrey

8. Topic

   brain cancer

9. Study Population

   Participants are 18 years old with diagnosis of primary brain tumor or metastatic brain tumor, at least 6 months since finishing radiation therapy to the brain, and more than 2 weeks since donepezil, methylphenidate, or EGb761.

10. Funded by

    Cancer Trials Support Unit

11. Phase

    Phase 3 clinical trial

12. Performed by

    Clinical Protocol & Data Management Shared Resource