eagle-i University of Hawaii at ManoaUniversity of Hawaii at Manoa
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Paclitaxel with or without carboplatin and/or bevacizumab followed by doxorubicin and cyclophosphamide in treating patients with breast cancer that can be removed by surgery

eagle-i ID

http://hawaii.eagle-i.net/i/00000130-d3a3-7ba5-9953-50a980000000

Resource Type

  1. Clinical trial

Properties

  1. ClinicalTrials.gov url
    http://www.clinicaltrials.gov/ct2/show/NCT00861705?term=NCT00861705&rank=1
  2. Intervention
    Carboplatin
  3. Intervention
    Bevacizumab
  4. Intervention
    Doxorubicin
  5. Intervention
    Cyclophosphamide
  6. Intervention
    Paclitaxel
  7. Intervention
    Antineoplastic combined chemotherapy
  8. Resource Description
    This randomized phase II trial is studying how well giving paclitaxel with or without carboplatin and/or bevacizumab followed by doxorubicin and cyclophosphamide works in treating patients with breast cancer that can be removed by surgery.
  9. Additional Name
    Randomized phase II 2 x 2 factorial trial of the addition of carboplatin +/- bevacizumab to neoadjuvant weekly paclitaxel followed by dose-dense ACc in hormone receptor-poor/HER2-negative resectable breast cancer
  10. Contact
    Berenberg, Jeffrey
  11. PI
    Berenberg, Jeffrey
  12. Topic
    breast cancer
  13. Study Population
    At least 18 years old Stage II or stage IIIA breast cancer Measurable disease HER2-negative, estrogen receptor-negative (ER-), and progesterone receptor-negative (PR-) tumor More than 4 weeks since surgery No previous chemotherapy, hormone therapy, or radiation therapy for this cancer For more information about the eligibility criteria for this trial, refer to the Health Professional version. For more information about the eligibility criteria for this trial, refer to the Health Professional version.
  14. Funded by
    Cancer Trials Support Unit
  15. Phase
    Phase 2 clinical trial
  16. Performed by
    Clinical Protocol & Data Management Shared Resource
 
RDFRDF
 
Provenance Metadata About This Resource Record
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The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016