Substudy of the IBCSG 24-02/ SOFT trial to investigate estrogen suppression for patients participating in Arms B and C of the IBCSG 24-02/ SOFT trial

eagle-i ID

Resource Type

Properties

1. ClinicalTrials.gov url

   http://www.clinicaltrials.gov/ct2/show/NCT00975676?term=IBCSG-24-02&rank=1

2. Resource Description

   This study is being done to see if shutting down the ovaries plus giving tamoxifen is better at preventing the return of breast cancer than just tamoxifen alone in premenopausal women. It will also test whether a newer hormone drug called exemustane plus suppression of the ovaries is better than tamoxifen plus suppression of the ovaries. In addition the side effects of these different treatments will be studied.

3. Contact

   Berenberg, Jeffrey

4. PI

   Berenberg, Jeffrey

5. Topic

   breast disease

6. Study Population

   Premenopausal women with resected breast cancer with ER- and/or PR-positive tumors. They must have estradiol levels in the premenopausal range after receiving chemotherapy and no metastatic disease.

7. Website(s)

   http://www.cancer.gov/clinicaltrials/search/view?cdrid=650841&version=healthprofessional

8. Funded by

   Cancer Trials Support Unit

9. Phase

   Phase 3 clinical trial

10. Performed by

    Clinical Protocol & Data Management Shared Resource