Clinical trial
clinical trial
Risk-based treatment for pediatric non-rhabdomyosarcoma soft tissue sarcomas (NRSTS)
Contact
has contact
has_contact
Berenberg, Jeffrey
PI
has PI
has_PI
Wilkinson, Robert, M.D.
Topic
has topic
has_topic
connective tissue cancer
Funded by
funded by
funded_by
Children's Oncology Group
Phase
Phase 3 clinical trial
has phase
has_phase
Phase 3
Performed by
human study performed by
human_study_performed_by
Clinical Protocol & Data Management Shared Resource
http://www.curesearch.org/ArticleView2.aspx?id=9113&l=8673
Website(s)
has URL
has_url
Antineoplastic combined chemotherapy protocols
Additional Topic(s)
has_subject_area
Radiotherapy
Studies done in both children and adults with Non-rhabdomyosarcoma soft tissue sarcomas have shown that the amount of treatment a patient needs may be based on the “risk group” of the tumor. Tumors are assigned a risk group based on features that influence how they behave.
For NRSTS, the risk group is based on the type of cells in the tumor (the grade of the tumor), the size of the tumor, if the tumor has spread to other areas of the body, and how much of the tumor can be taken out by surgery.
Patients with tumors in the low risk group may be cured with mild treatment, in some cases only surgery.
Patients with tumors in the intermediate and high-risk groups may need more treatment, including anti-cancer drugs (chemotherapy) and high energy X-ray therapy (radiation therapy).
This study is being done to find out:
if treatment based on each subject's level of risk will get rid of the tumor and
if lessening the treatment for lower risk subjects will decrease the side effects of treatment and still get rid of the tumor.
Resource Description
resource_description
This study is for patients less than 30 years of age at the time of the biopsy that established the diagnosis of NRSTS. Patients < 2 years of age with infantile fibrosarcoma are not eligible for this study. There must be a diagnosis of NRSTS that is confirmed by COG designated pathologists.
Study Population
study population
has_study_population
2011-06-27T18:02:08.928-05:00
awendicke (Annemarie Wendicke)
2015-08-17T11:58:17.988-05:00
workflow state
Published
tjohnson (Tenille Johnson)
Interventional study
Research project
research project
Human Study
human study
human study
planned process
planned process
Quantitative human study
process
occurrent
entity