Treatment of high risk renal tumors

eagle-i ID

Resource Type

Properties

1. ClinicalTrials.gov url

   http://www.clinicaltrials.gov/ct2/show/NCT00335556?term=NCT00335556&rank=1

2. Intervention

   Carboplatin

3. Intervention

   Cyclophosphamide

4. Intervention

   Doxorubicin hydrochloride

5. Intervention

   Etoposide

6. Intervention

   Irinotecan hydrochloride

7. Intervention

   Vincristine sulfate

8. Intervention

   Radiation

9. Intervention

   Conventional surgery

10. Additional Topic(s)

    Antineoplastic Combined Chemotherapy Protocols

11. Additional Topic(s)

    Radiotherapy

12. Resource Description

    Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving combination chemotherapy together with radiation therapy before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. This phase II trial is studying how well combination chemotherapy, radiation therapy, and/or surgery work in treating patients with high-risk kidney tumors.

13. Contact

    Berenberg, Jeffrey

14. PI

    Wilkinson, Robert, M.D.

15. Topic

    kidney cancer

16. Study Population

    Persons 30 years old or younger who meet other tumor-related criteria.

17. Funded by

    Children's Oncology Group

18. Phase

    Phase 2 clinical trial

19. Performed by

    Clinical Protocol & Data Management Shared Resource