Clinical trial
clinical trial
Study of conformal radiotherapy in patients with low-grade gliomas
Intervention
Radiologic intervention
Intervention Type
radiologic intervention
has_intervention
Small-field radiation therapy
radiologic intervention
Small-field radiation therapy
Intervention
intervention
planned process
planned process
process
occurrent
entity
Contact
has contact
has_contact
Berenberg, Jeffrey
PI
has PI
has_PI
Wilkinson, Robert, M.D.
Topic
has topic
has_topic
malignant glioma
Funded by
funded by
funded_by
Children's Oncology Group
Phase
Phase 2 clinical trial
has phase
has_phase
Phase 2
Performed by
human study performed by
human_study_performed_by
Clinical Protocol & Data Management Shared Resource
http://www.curesearch.org/ArticleView2.aspx?id=7328&l=8673
Website(s)
has URL
has_url
Older children with low grade gliomas that have come back after surgery or are causing problems are often treated with radiation therapy. Younger children are usually treated first with chemotherapy, but if the tumor comes back following completion of therapy, then they often receive radiation therapy as well. Radiation therapy can cause severe side effects. New types of radiation therapy can treat a smaller area of the brain and doctors think that patients who receive this type of radiation might have fewer side effects.
The purpose of this study is to test the safety and effectiveness of this “smaller field radiation” in patients with low grade gliomas. This study will also try to determine if the results of a special test performed on the removed tumor tissue predict how the tumor may respond to radiation. Finally, this study will also evaluate the functional status and quality-of-life of children with low grade gliomas who receive this treatment.
Resource Description
resource_description
Patients enrolled on this study must be > 3 years and < 21 years at the time of diagnosis.
Study Population
study population
has_study_population
2011-06-22T20:32:33.703-05:00
awendicke (Annemarie Wendicke)
2011-11-21T15:49:57.987-06:00
workflow state
Published
nvasilevsky
shoffmann
Interventional study
Research project
research project
Human Study
human study
human study
planned process
planned process
Quantitative human study
process
occurrent
entity