Aortic banding service

eagle-i ID

Resource Type

Properties

1. Resource Description

   "One of the most commonly used surgical intervention for pressure-overload induced hypertrophy is coarction of the ascending aorta i.e. aortic banding. This system has been very well characterized and proven to be highly reproducible with a low mortality rate of 10-20% or less in experienced hands. Aortic banding is an excellent model system to evaluate the process of development of left ventricular hypertrophy in response to hemodynamic stress. Furthermore, after several months, a subset of animals progresses into heart failure." (http://www2.jabsom.hawaii.edu/mousecore/)

2. Contact

   Boisvert, William, Ph.D.

3. Service Provided by

   COBRE Mouse Phenotyping Core

4. Website(s)

   http://www2.jabsom.hawaii.edu/mousecore/

5. Related Technique

   Small animal surgery