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Aortic banding service
eagle-i ID
http://hawaii.eagle-i.net/i/0000012b-36bb-3b1d-2f73-b43980000003
Resource Type
Properties
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Resource Description
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"One of the most commonly used surgical intervention for pressure-overload induced hypertrophy is coarction of the ascending aorta i.e. aortic banding. This system has been very well characterized and proven to be highly reproducible with a low mortality rate of 10-20% or less in experienced hands. Aortic banding is an excellent model system to evaluate the process of development of left ventricular hypertrophy in response to hemodynamic stress. Furthermore, after several months, a subset of animals progresses into heart failure." (http://www2.jabsom.hawaii.edu/mousecore/)
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Contact
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Boisvert, William, Ph.D.
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Service Provided by
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COBRE Mouse Phenotyping Core
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Website(s)
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http://www2.jabsom.hawaii.edu/mousecore/
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Related Technique
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Small animal surgery
